Ammonificins C and D, Hydroxyethylamine Chromene Derivatives from a Cultured Marine Hydrothermal Vent Bacterium, Thermovibrio ammonificans
نویسندگان
چکیده
Two hydroxyethylamine chroman derivatives, ammonificins A (1) and B (2), were isolated from the marine hydrothermal vent bacterium Thermovibrio ammonificans. The molecular structures of these compounds were determined using a combination of NMR, mass spectrometry, and CD analyses. Biological activities were determined using an antimicrobial assay and the patented ApopScreen cell-based screen for apoptosis induction and potential anticancer activity. To our knowledge, this is the first report of secondary metabolites from the marine hydrothermal vent bacterium T. ammonificans.
منابع مشابه
Ammonificins A and B, Hydroxyethylamine Chroman Derivatives from a Cultured Marine Hydrothermal Vent Bacterium, Thermovibrio ammonificans
Center for Marine Biotechnology, Institute of Marine and Coastal Sciences, Rutgers, The State UniVersity of New Jersey, New Jersey 08901-8521, Department of Biology, Rider UniVersity, 2083 LawrenceVille Road, LawrenceVille, New Jersey 08648, Center for AdVanced Biotechnology and Medicine, Department of Molecular Biology and Biochemistry, Rutgers, The State UniVersity of New Jersey, 679 Hoes Lan...
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